Description

Fmoc-VAP-MMAE is a agent-linker conjugates for ADC. Fmoc-VAP-MMAE consists of an ADC linker and a tubulin inhibitor MMAE (HY-15162), with a protective Fmoc group[1].–Applications-Cancer-programmed cell death-Formula-C70H98N8O13-Citation–References-[1]Jackson David Y et al. Novel antibody-drug conjugates and related compounds, compositions, and methods of use. Patent. WO2016064749. -CASNumber-1912408-91-3-MolecularWeight-1259.57-Compound Purity–SMILES-O=C(N1[C@](CCC1)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](C)NC([C@H](C(C)C)NC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O)=O)=O)=O)=O)=O-Research_Area-Others-Solubility-10 mM in DMSO-Target-Drug-Linker Conjugates for ADC-Isoform–Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related