Description

OPSS-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C26H36N6O5S2-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber–MolecularWeight-576.73-Compound Purity–SMILES-O=C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)CCSSC2=NC=CC=C2-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Cleavable Linker;Disulfide Cleavable Linker;Protease Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related