Description

MC(C5)-Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C20H32N6O6-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber-2504147-59-3-MolecularWeight-452.50-Compound Purity–SMILES-OC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC(CCCCN1C(C=CC1=O)=O)=O)=O)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Cleavable Linker;Protease Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related