Description

TCO-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C24H38N2O10-Citation–References-[1]Jung S, et al. An integrated approach for enhanced protein conjugation and capture with viral nanotemplatesand hydrogel microparticle platforms via rapid bioorthogonal reactions. Langmuir. 2014 Jul 8;30(26):7762-70.-CASNumber-1613439-69-2-MolecularWeight-514.57-Compound Purity-99.58-SMILES-O=C(OC1CC/C=CCCC1)NCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O-Research_Area-Cancer-Solubility-DMSO : 50 mg/mL (ultrasonic)-Target-ADC Linker;PROTAC Linkers-Isoform-Cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related