Description

N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C29H30INO12-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber-114390-30-6-MolecularWeight-711.45-Compound Purity–SMILES-COC1=CC=CC2=C1C(C3=C(C2=O)C(O)=C4C([C@@H](O[C@@H]5O[C@@H](C)[C@@H](O)[C@@H](NC(CI)=O)C5)C[C@@](C(CO)=O)(O)C4)=C3O)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related