Description

DMAC-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C16H19N3O8S3-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber-663599-07-3-MolecularWeight-477.53-Compound Purity–SMILES-O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCSSC2=NC=C(C(N(C)C)=O)C=C2-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Cleavable Linker;Disulfide Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related