Description

BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.–20°C, 3 years (Powder)-Applications-Cancer-programmed cell death-Formula-C29H46N4O7S-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber-1263166-92-2-MolecularWeight-594.76-Compound Purity-95.0-SMILES-[H][C@@]12[C@@](CCC#CCC2)([H])[C@@H]1COC(NCCOCCOCCOCCNC(CCCC[C@@H]3SC[C@H](N4)[C@@H]3NC4=O)=O)=O-Research_Area-Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)-Target-ADC Linker-Isoform-Non-cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related