Description

Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG9-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.–20°C, 3 years; 4°C, 2 years (Powder)-Applications-COVID-19-immunoregulation-Formula-C21H41N3O11-Citation–References-[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.-CASNumber-1670249-37-2-MolecularWeight-511.56-Compound Purity-96.0-SMILES-O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]-Research_Area-Cancer; Inflammation/Immunology-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related