Propargyl-PEG7-NHS ester-Get quote

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SKU: HY-130381-Get quote Category: Tags: ,

Description

Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG7-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.–Applications-Cancer-programmed cell death-Formula-C22H35NO11-Citation–References-[1]Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1.-CASNumber-2093152-77-1-MolecularWeight-489.51-Compound Purity–SMILES-C#CCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Alkyl/ether Linkers;Cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related

Brand

MEDCHEM EXPRESS

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