Description

Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG7-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG7-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.–20°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C16H34N4O7-Citation–References-[1]Kevin W. Gillman, et al. Macrocyclic peptides useful as immunomodulators. WO2016077518A1.-CASNumber-1333154-77-0-MolecularWeight-394.46-Compound Purity-95.0-SMILES-NCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]-Research_Area-Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related