Phe-Lys(Trt)-PAB-1 mg

Description

Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C41H44N4O3-Citation–References-[1]Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.-CASNumber-1116085-99-4-MolecularWeight-640.81-Compound Purity–SMILES-O=C(N)[C@H](CCCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)N(C([C@H](CC4=CC=CC=C4)N)=O)C5=CC=C(CO)C=C5-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Cleavable Linker;Protease Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related