Description

(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody agent conjugates (ADCs) toxin.–Applications-Cancer-programmed cell death-Formula-C36H28N6O4-Citation–References-[1]Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35.-CASNumber-128300-15-2-MolecularWeight-608.65-Compound Purity–SMILES-O=C(N1C2=CC=C3NC(C(N4C5=CC=C6NC(C(N7C[C@](C8)([H])[C@]98C=CC=CC=CC(C=C79)=O)=O)=CC6=C5CC4)=O)=CC3=C2CC1)N-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Cytotoxin;DNA Alkylator/Crosslinker-Isoform-Duocarmycins-Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage-MCE Product type-ADC Related