Description

[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively[1].—Neuroscience-Neuromodulation–C80H109N21O13S—-[1]S H Buck, et al. Agonist and antagonist binding to tachykinin peptide NK-2 receptors. Life Sci. 1988;42(26):2701-8.–100930-11-8–1604.92—-CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CNC2=CC=CC=C12)NC([C@H](CC3=CC=CC=C3)NC([C@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H]4N(CCC4)C([C@H](CCCCN)NC([C@H](NC([C@@H](N)CCCNC(N)=N)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)CC7=CNC8=CC=CC=C78)=O)=O)=O)=O–Neurological Disease–10 mM in DMSO–Neurokinin Receptor–NK1;NK2;NK3–GPCR/G Protein;Neuronal Signaling–Peptides