Description

NH2-AKK-COOH, a synthetic tripeptide, is an ACE inhibitor, with IC50s of 0.090 μM, 0.178 μM, and 420.89 μM when FAPGG, HHL, and angiotensin-I are used as substrate respectively[1].—Neuroscience-Neuromodulation–C15H31N5O4—-[1]Henda YB, et, al. Measuring angiotensin-I converting enzyme inhibitory activity by micro plate assays: comparison using marine cryptides and tentative threshold determinations with captopril and losartan. J Agric Food Chem. 2013 Nov 13;61(45):10685-90.–158837-92-4–345.44—-O=C(N[C@H](C(O)=O)CCCCN)[C@H](CCCCN)NC([C@@H](N)C)=O–Cardiovascular Disease–H2O–Angiotensin-converting Enzyme (ACE)—-Metabolic Enzyme/Protease–Peptides