Description

[D-Asn5]-Oxytocin possesses very low specific oxytocic and vasodepressor activities. By cumulative dose-response studies for oxytocic activity, [D-Asn5]-Oxytocin has similar intrinsic activity to oxytocin[1].—Metabolism-protein/nucleotide metabolism–C43H66N12O12S2—-[1]Dutta AS, et al. Synthesis and pharmacological activity of 4-d-glutamine-oxytocin, 5-d-asparagine-oxytocin, and 4-d-glutamine-5-d-asparagine-oxytocin. J Med Chem. 1966;9(4):497-499.–5754-53-0–1007.19—-O=C([C@H]1NC([C@H](NC([C@@H](NC([C@](NC([C@@H](NC([C@H](CSSC1)N)=O)CC2=CC=C(C=C2)O)=O)([H])[C@@H](C)CC)=O)CCC(N)=O)=O)CC(N)=O)=O)N3[C@@H](CCC3)C(N[C@@H](CC(C)C)C(NCC(N)=O)=O)=O–Endocrinology–10 mM in DMSO–Others—-Others–Peptides