Description

Slotoxin, a peptide from Centruroides noxius Hoffmann scorpion venom, blocks high conductance calcium-activated potassium channel, with Kd of 1.5 nM[1].—Neuroscience-Neuromodulation–C177H275N47O50S7—-[1]Garcia-Valdes J, et al. Slotoxin, αKTx1.11, a new scorpion peptide blocker of MaxiK channels that differentiates between α and α+β (β1 or β4) complexes. FEBS Lett. 505 (3): 369–73.—-4085.82—-O=C([C@@H](N)[C@@H](C)O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]2CCCCN)=O)=O)CCCNC(N)=N)=O)CC(O)=O)=O)C(C)C)=O)=O)CC3=CC=CC=C3)=O)C)=O)C)=O)CCCCN)=O)CSSC[C@H](NC4=O)C(N[C@H](C(N[C@H](C(O)=O)C(C)C)=O)CC5=CC=C(O)C=C5)=O)=O)CCC1)=O)C)=O)CC6=CNC7=CC=CC=C67)=O)CSSC[C@H](NC8=O)C(N[C@H]4CCCCN)=O)=O)CCC(O)=O)=O)CCCCN)=O)CO)=O)C(C)C)=O)[C@@H](C)O)=O)CSSC[C@H](NC2=O)C(N[C@H](C(NCC(N[C@H](C(N[C@H]8CCCCN)=O)CCCCN)=O)=O)CCSC)=O)=O)CC(O)=O)=O)C(C)C)=O)CC(O)=O)=O)[C@H](CC)C)=O)CC9=CC=CC=C9–others–10 mM in DMSO–Potassium Channel—-Membrane Transporter/Ion Channel–Peptides