G-Protein antagonist peptide (TFA)-1 mg

Description

G-Protein antagonist peptide TFA is a truncated substance P-related peptide, competes with receptor for G protein binding. G-Protein antagonist peptide TFA inhibits the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis[1].–80°C, 2 years; -20°C, 1 year (Powder, stored under nitrogen, away from moisture)–Neuroscience-Neuromodulation–C59H65F3N12O11S—-[1]Mukai H, et al. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J Biol Chem. 1992;267(23):16237-16243.—-1207.28–98.91–CSCC[C@@H](C(N)=O)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC5=CC=CC=C5)NC([C@@H](CC6=CNC7=C6C=CC=C7)NC([C@H](CCC(N)=O)NC([C@H](CC8)NC8=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F–Endocrinology–DMSO : 100 mg/mL (ultrasonic)–Adrenergic Receptor;mAChR–mAChR2–GPCR/G Protein;Neuronal Signaling–Peptides