Stressin I (TFA)-5 mg

Description

Stressin I (Cyclo(31-34)[DPhe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41)) TFA is a potent CRF1 receptor selective agonist, Ki is 1.7 nM. Stressin I induces an increase in adrenocorticotropic hormone (ACTH) levels in rats[1][1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)—-C203H337N57O56.xC2HF3O2—-[1]Rivier J, et al. Stressin1-A, a potent corticotropin releasing factor receptor 1 (CRF1)-selective peptide agonist. J Med Chem. 2007 Apr 5;50(7):1668-74. [Content Brief]—-4472.20 (free base)–98.38–CCCC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCC(NCCCC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCC)=O)CC(C)C)=O)CCCCN)=O)CCCNC(N)=N)=O)NC([C@@H](NC([C@@H](NC1=O)CC2=CNC=N2)=O)CO)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)C)=O)CC(C)C)=O)CCC(N)=O)=O)CCC(O)=O)=O)C)=O)CCCNC(N)=N)=O)C)=O)NC([C@@H](NC([C@@H](NC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@H]([C@H](O)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)NC([C@@H]3CCCN3C([C@@H]4CCCN4C(C)=O)=O)=O)=O)CO)=O)CC(C)C)=O)CC(O)=O)=O)CC(C)C)=O)=O)CC5=CC=CC=C5)=O)CC6=CNC=N6)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)=O)CC(C)C)=O)CCC(O)=O)=O.xOC(C(F)(F)F)=O–Endocrinology–H2O : 1.98 mg/mL (ultrasonic;adjust pH to 3 with HCl)–CRFR—-GPCR/G Protein–Peptides