Description
des-Gln14-Ghrelin TFA is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM[1].—Metabolism-protein/nucleotide metabolism–C142H237N43O40.xC2HF3O2—-[1]H Hosoda, et al. Purification and Characterization of Rat des-Gln14-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor. J Biol Chem. 2000 Jul 21;275(29):21995-2000.—-3186.67 (free acid)—-OC(C(F)(F)F)=O.O=C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N2[C@@H](CCC2)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)[C@H]3N(CCC3)C([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H]4N(CCC4)C([C@H](CO)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](COC(CCCCCCC)=O)NC([C@H](CO)NC(CN)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O–Metabolic Disease–10 mM in DMSO–GHSR—-GPCR/G Protein–Peptides




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