GR 94800-Get quote

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Description

GR 94800 is a potent and selective NK2 receptor peptide antagonist, with pKB values of 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively[1][2].—Neuroscience-Neuromodulation–C49H61N9O8—-[1]A B McElroy, et al. Highly potent and selective heptapeptide antagonists of the neurokinin NK-2 receptor. J Med Chem. 1992 Jul 10;35(14):2582-91.|[2]M A Matuszek, et al. An investigation of tachykinin NK2 receptor subtypes in the rat. Eur J Pharmacol. 1998 Jul 3;352(1):103-9.|[3]Stephen D Tichenor, et al. Excitatory motor innervation in the canine rectoanal region: role of changing receptor populations. Br J Pharmacol. 2002 Dec;137(8):1321-9.–141636-65-9–904.06—-[Bz-AA-{D-Trp}-F-{D-Pro}-P-{Nle}-NH2]–Neurological Disease–10 mM in DMSO–Neurokinin Receptor–NK2–GPCR/G Protein;Neuronal Signaling–Peptides

Brand

MEDCHEM EXPRESS