Calcineurin autoinhibitory peptide-1 mg

Description

Calcineurin autoinhibitory peptide is a selective inhibitor of Ca2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. Calcineurin autoinhibitory peptide could protect neurons from excitatory neuronal death[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–Neuroscience-Neuromodulation–C124H205N39O39S2—-[1]Hashimoto Y, et, al. Identification of an autoinhibitory domain in calcineurin. J Biol Chem. 1990 Feb 5; 265(4): 1924-7.|[2]Terada H, et, al. Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem. 2003 Dec; 87(5): 1145-51.–148067-21-4–2930.32–99.96–O=C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CCSC)C(N2[C@@H](CCC2)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H]3N(CCC3)C([C@H](CCSC)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC([C@H](CC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O–Neurological Disease–H2O : 100 mg/mL (ultrasonic)–Phosphatase—-Metabolic Enzyme/Protease–Peptides