Description

GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist[1]. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals[2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)–Metabolism-protein/nucleotide metabolism–C40H59N7O6S—-[1]Sakurada C, et al. Spinal actions of GR73632, a novel tachykinin NK1 receptor agonist. Peptides. 1999;20(2):301-4.|[2]Costantini VJ, et al. The NK1 receptor antagonist aprepitant attenuates NK1 agonist-induced scratching behaviour in the gerbil after intra-dermal, topical or oral administration. Exp Dermatol. 2015 Apr;24(4):312-4.–133156-06-6–766.00–99.98–NCCCCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(N([C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)C)=O)=O)=O)=O–Neurological Disease; Endocrinology–10 mM in DMSO–Neurokinin Receptor–NK1–GPCR/G Protein;Neuronal Signaling–Peptides