WRW4 (TFA)-Get quote

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Description

WRW4 TFA, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC50 of 0.23 μM. WRW4 TFA specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide[1].—Neuroscience-Neuromodulation–C63H66F3N15O8—-[1]Bae YS, et al. Identification of peptides that antagonize formyl peptide receptor-like 1-mediated signaling. J Immunol. 2004;173(1):607-614.—-1218.29—-O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CC7=CNC8=CC=CC=C78)C(N)=O)=O)=O)=O)=O)[C@H](CC9=CNC=CC=CC=C9)N.OC(C(F)(F)F)=O–Neurological Disease–10 mM in DMSO–Formyl Peptide Receptor (FPR)—-GPCR/G Protein–Peptides

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MEDCHEM EXPRESS

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