Description

A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor), which is an Ang1-7 receptor distinct from the classical AngII.–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–COVID-19-immunoregulation–C39H60N12O11—-[1]Abuohashish HM, et al. Angiotensin (1-7) ameliorates the structural and biochemical alterations of ovariectomy-induced osteoporosis in rats via activation of ACE-2/Mas receptor axis. Sci Rep. 2017 May 23;7(1):2293.|[2]Abuohashish HM, et al. ACE-2/Ang1-7/Mas cascade mediates ACE inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats. Biomed Pharmacother. 2017 Aug;92:58-68.|[3]Yan WF, et al. Effects and related mechanism of angiotensin-(1-7) on Toll-like receptor 4-mediated oxidative stress in human umbilical vein endothelial cells. Zhonghua Xin Xue Guan Bing Za Zhi. 2017 Mar 24;45(3):223-229.–159432-28-7–872.97–98.59–O=C(N[C@]([C@@H](C)CC)([H])C(N[C@H](C(N[C@H](C)C(O)=O)=O)CC1=CNC=N1)=O)[C@@H](NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)CC2=CC=C(O)C=C2–Cardiovascular Disease; Endocrinology–0.1 M HCL : 25 mg/mL (ultrasonic;adjust pH to 1 with HCl)|H2O : 5 mg/mL (ultrasonic)–Angiotensin Receptor–AT1 Receptor;AT2 Receptor–GPCR/G Protein–Peptides