Description

Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment[1].—Cancer-programmed cell death–C6H12N2O4Se2—-[1]Eva Ari Wahyuni, et al. Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells. Chem Biol Interact. 2022 Sep 25:365:110046.–2897-21-4–334.09—-NC(C[Se][Se]CC(C(O)=O)N)C(O)=O–Cancer–10 mM in DMSO–Endogenous Metabolite—-Metabolic Enzyme/Protease–Peptides