Description

TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage[1].—–C45H51N9Na2O11S—-[1]Toshifumi Watanabe, et al. TAK-044: An Endothelin Receptor Antagonist. , 14(1), 36–46.–157380-72-8–971.98—-O=C([C@@H](NC([C@H](C1=CC=CS1)NC([C@@H](NC([C@@H](NC([C@H](NC2=O)CC(O[Na])=O)=O)CC(N3CCN(C4=CC=CC=C4)CC3)=O)=O)CC(O[Na])=O)=O)=O)CC(C)C)N[C@@H]2CC5=CNC6=CC=CC=C56–Cardiovascular Disease–10 mM in DMSO–Endothelin Receptor—-GPCR/G Protein–Peptides