Description

Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA[1].—–C33H42N6O13—-[1]Yu-Hsuan Lan, et al. Death receptor 5-mediated TNFR family signaling pathways modulate γ-humulene-induced apoptosis in human colorectal cancer HT29 cells. Oncol Rep. 2011 Feb;25(2):419-24.–348079-18-5–730.72—-O=C(OCC1=CC=CC=C1)N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(NC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)=O)=O–Cancer–10 mM in DMSO–Caspase—-Apoptosis–Peptides