Description

YO-PRO-1 (Oxazole yellow) is a carbocyanine monomer and DNA green fluorescent dye that is not permeable to normal animal cell membranes but is permeable to the cell membranes of apoptotic and necrotic cells. YO-PRO-1 is commonly used for the detection of apoptosis and necrosis. YO-PRO-1 has a high affinity for DNA and is essentially non-fluorescent when not bound to DNA. When apoptosis occurs, the permeability of the cell membrane changes. YO-PRO-1 can enter apoptotic cells and bind to DNA and emit bright green fluorescence. Therefore, YO-PRO-1 is often used together with propidium iodide (PI) to analyze and identify apoptotic and necrotic cells.–Applications–Formula-C24H29I2N3O-Citation–References–CASNumber-152068-09-2-MolecularWeight-629.32-Compound Purity–SMILES-C[N+](CCC[N+]1=C2C=CC=CC2=C(/C=C3OC4=CC=CC=C4N3C)C=C1)(C)C.[I-].[I-]-Research_Area-Others-Solubility-10 mM in DMSO-Target-Fluorescent Dye-Isoform–Pathway-Others-MCE Product type-Dye Reagents