Description

Y4R agonist-1 is a Y4R agonist with a Ki of 0.048 nM.—–C51H80N18O11—-[1]Konieczny A, et al. N-Terminus to Arginine Side-Chain Cyclization of Linear Peptidic Neuropeptide Y Y4 Receptor Ligands Results in Picomolar Binding Constants. J Med Chem. 2021 Nov 8. –2757328-51-9–1121.29—-NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CCCNC2=N)NC([C@@H](NC([C@H](CCCNC(N)=N)NC(CCC(NCCCCNC(N2)=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)=O)=O)=O–Others–10 mM in DMSO–Others—-Others–Peptides