Description

Tizoxanide-d4 is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities[1][2].-4°C (Powder, sealed storage, away from moisture and light)-Applications-COVID-19-anti-virus-Formula-C10H3D4N3O4S-Citation–References-[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Korba BE, et al. Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication. Antiviral Res. 2008 Jan;77(1):56-63.|[3]Ashton LV, et al. In Vitro Susceptibility of Canine Influenza A (H3N8) Virus to Nitazoxanide and Tizoxanide. Vet Med Int. 2010 Aug 12;2010. pii: 891010.|[4]Korba BE, et al. Potential for hepatitis C virus resistance to nitazoxanide or tizoxanide. Antimicrob Agents Chemother. 2008 Nov;52(11):4069-71.|[5]Trabattoni D, et al. Thiazolides Elicit Anti-Viral Innate Immunity and Reduce HIV Replication. Sci Rep. 2016 Jun 2;6:27148.-CASNumber-1246817-56-0-MolecularWeight-269.27-Compound Purity-99.79-SMILES-O=[N+]([O-])C1=CN=C(S1)NC(C2=C(C([2H])=C([2H])C([2H])=C2[2H])O)=O-Research_Area-Infection-Solubility-10 mM in DMSO-Target-Autophagy;Bacterial;HIV;Isotope-Labeled Compounds-Isoform–Pathway-Anti-infection;Autophagy;Others-MCE Product type-Isotope-Labeled Compounds