Description

Tetrazine-PEG7-amine hydrochloride is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG7-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.-4°C (Powder, sealed storage, away from moisture)-Applications-Cancer-programmed cell death-Formula-C26H43ClN6O8-Citation–References-[1]Beck A, et, al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber–MolecularWeight-603.11-Compound Purity-99.16-SMILES-O=C(CCOCCOCCOCCOCCOCCOCCOCCN)NCC(C=C1)=CC=C1C2=NN=CN=N2.Cl-Research_Area-Cancer-Solubility-DMSO : 200 mg/mL (ultrasonic)-Target-ADC Linker-Isoform–Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related