Description

Tetrazine-PEG4-amine (hydrochloride) is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetrazine-PEG4-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.–20°C (Powder, sealed storage, away from moisture)-Applications-Cancer-programmed cell death-Formula-C20H31ClN6O5-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber-2752945-36-9-MolecularWeight-470.95-Compound Purity-95.15-SMILES-NCCOCCOCCOCCOCCC(NCC1=CC=C(C2=NN=CN=N2)C=C1)=O.[H]Cl-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related