Description

Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis.—COVID-19-immunoregulation–C47H64N8O11—-[1]Monsarrat C, et al. Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J Med Chem. 2021 Nov 22. –2756997-82-5–917.06—-CC(C[C@@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)NC([C@@H](N(C([C@@H](NC([C@@H](NC(/C=C/C3=CC=CN=C3)=O)CCC(N)=O)=O)CC4CCCCC4)=O)C)CC(O)=O)=O)C–Infection–10 mM in DMSO–Bacterial—-Anti-infection–Peptides