Description

SR 42128 is a potent renin inhibitor. SR 42128 potently inhibits primate renins whereas other animal renins are much less inhibited[1].—–C39H65N5O9—-[1]M De Claviere, et al. In vitro and in vivo inhibition of human and primate renin by a new potent renin inhibitor: SR 42128. J Cardiovasc Pharmacol. 1985:7 Suppl 4:S58-61.–98092-14-9–747.96—-C[C@@H](C(NC(C[C@H](O)[C@@H](N)CC(C)C)=O)=O)N(C([C@H](CCCC)NC([C@H](CC1=CC=CC=C1)NC(CC(C)C)=O)=O)=O)[C@H]([C@@H](O)CC(O)=O)CC(C)C–Cardiovascular Disease–10 mM in DMSO–Renin—-Metabolic Enzyme/Protease–Peptides