Description

Seco-Duocarmycin SA is a DNA alkylator, and is used as an ADC cytotoxin[1].–Applications-Cancer-programmed cell death-Formula-C25H24ClN3O7-Citation–References-[1]Lutz F. Tietze, et al. A Concise and Efficient Synthesis of seco-Duocarmycin SA. European Journal of Organic Chemistry 2003 (3), 562-566.-CASNumber-144667-38-9-MolecularWeight-513.93-Compound Purity–SMILES-O=C(C1=CC2=C3C(N(C(C(N4)=CC5=C4C(OC)=C(OC)C(OC)=C5)=O)CC3CCl)=CC(O)=C2N1)OC-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Cytotoxin;DNA Alkylator/Crosslinker-Isoform-Duocarmycins-Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage-MCE Product type-ADC Related