Description

Seco-DUBA hydrochloride is a toxin for ADC drug SYD985[1].–Applications-COVID-19-immunoregulation-Formula-C29H23ClN4O4.xHCl-Citation–References-[1]Ronald C Elgersma, et al. Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody-Drug Conjugate SYD985. Mol Pharm. 2015 Jun 1;12(6):1813-35.-CASNumber-1795733-93-5-MolecularWeight-N/A-Compound Purity–SMILES-ClC[C@H]1C2=C(C=C(C3=CC=CC(C)=C32)O)N(C1)C(C4=CN(C=C(C=C5)NC(C6=CC=C(C=C6)O)=O)C5=N4)=O.Cl[H].[x]-Research_Area-Cancer; Inflammation/Immunology-Solubility-DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)-Target-ADC Cytotoxin-Isoform–Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related