RFRP-3(human)-5 mg

Description

RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–Neuroscience-Neuromodulation–C45H72N14O10—-[1] Iain J Clarke, et al. Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion. Endocrinology–311309-27-0–969.14–99.21–O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H]2N(C([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H]3N(C([C@H](C(C)C)N)=O)CCC3)=O)=O)=O)CCC2)=O)=O)=O–Neurological Disease–DMSO : ≥ 100 mg/mL–Neuropeptide Y Receptor—-GPCR/G Protein;Neuronal Signaling–Peptides