Description

Reversin 121 is a P-glycoprotein inhibitor. Reversin 121 increases the ATPase activity of MDR1. Reversin 121 reverses P-glycoprotein-mediated multidrug resistance. Reversin 121 can be used in the research of cancers[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)–Cancer-programmed cell death–C34H47N3O9—-[1]Hoffmann K, et al. Effects of the high-affinity Peptide reversin 121 on multidrug resistance proteins in experimental pancreatic cancer. Tumour Biol. 2008;29(6):351-8. |[2]Yabuki N, et al. Gene amplification and expression in lung cancer cells with acquired paclitaxel resistance. Cancer Genet Cytogenet. 2007 Feb;173(1):1-9. |[3]Kooij G, et al. P-glycoprotein acts as an immunomodulator during neuroinflammation. PLoS One. 2009 Dec 8;4(12):e8212. –174630-04-7–641.75–99.31–O=C(NCCCC[C@@H](C(OC(C)(C)C)=O)NC([C@@H](NC(OC(C)(C)C)=O)CC(OCC1=CC=CC=C1)=O)=O)OCC2=CC=CC=C2–Cancer–DMSO : 100 mg/mL (ultrasonic)–P-glycoprotein—-Membrane Transporter/Ion Channel–Peptides