Description

Rac1 Inhibitor W56 is a peptide containing residues 45-60 of Rac1. Rac1 Inhibitor W56 inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam[1].—Neuroscience-Neuromodulation–C74H117N19O23S—-[1]Gao Y, Xing J, et al. Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors [published correction appears in J Biol Chem. 2005 Jan 14;280(2):1704]. J Biol Chem. 2001;276(50):47530-47541.–1095179-01-3–1671.93—-O=C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N–Cancer–10 mM in DMSO–Ras—-GPCR/G Protein;MAPK/ERK Pathway–Peptides