Description

Quercetin GMP is Quercetin (HY-18085) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Quercetin is a flavonoid antioxidant, a PI3K inhibitor and a SIRT1 Activator[1][2][3][4][5][6].–Applications–Formula-C15H10O7-Citation–References-[1]Zhou C, Lin Y. Osteogenic differentiation of adipose-derived stem cells promoted by quercetin. Cell Prolif. 2014 Apr;47(2):124-32.|[2]Wattel A, et al. Flavonoid quercetin decreases osteoclastic differentiation induced by RANKL via a mechanism involving NF kappa B and AP-1. J Cell Biochem. 2004 May 15;92(2):285-95.|[3]Zhou Y, et al. The Effect of Quercetin on the Osteogenesic Differentiation and Angiogenic Factor Expression of Bone Marrow-Derived Mesenchymal Stem Cells. PLoS One. 2015 Jun 8;10(6):e0129605.|[4]Woo JT, et al. Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts. Biol Pharm Bull. 2004 Apr;27(4):504-9.|[5]Kim YJ, et al. Quercetin, a flavonoid, inhibits proliferation and increases osteogenic differentiation in human adipose stromal cells. Biochem Pharmacol. 2006 Nov 15;72(10):1268-78.|[6]Pang XG, et al. Quercetin Stimulates Bone Marrow Mesenchymal Stem Cell Differentiation through an Estrogen Receptor-Mediated Pathway. Biomed Res Int. 2018 Mar 15;2018:4178021. -CASNumber-117-39-5-MolecularWeight-302.24-Compound Purity–SMILES-OC1=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3C1=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Apoptosis;Autophagy;Mitophagy;PI3K;Reactive Oxygen Species-Isoform–Pathway-Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;PI3K/Akt/mTOR-MCE Product type-GMP Small Molecules