Purotoxin 1-Get quote

Description

Purotoxin 1 is a P2X3 receptor inhibitor. Purotoxin 1 shows antinociceptive properties in animal models of inflammatory pain. Purotoxin 1 can be isolated from the venom of the wolf spider Geolycosa sp[1].—COVID-19-immunoregulation–C155H249N51O47S8—-[1]Grishin EV, et al. Novel peptide from spider venom inhibits P2X3 receptors and inflammatory pain. Ann Neurol. 2010 May;67(5):680-3.–1396322-38-5–3835.47—-O=C(CN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CC3=CNC=N3)=O)[C@H](CC)C)=O)CC(O)=O)=O)CC(O)=O)=O)CSSC[C@H](NC4=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H]5CC(N)=O)=O)CC6=CC=C(O)C=C6)=O)=O)CO)=O)C)=O)CC(N)=O)=O)CSSC[C@H](NC5=O)C(N[C@H]2C(C)C)=O)=O)CCCCN)=O)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)=O)CCCCN)=O)CCC(O)=O)=O)C)=O)CSSC[C@H](NC1=O)C(N[C@H](C(NCC(N[C@H](C(N[C@H]4CCCCN)=O)CC(C)C)=O)=O)[C@@H](C)O)=O)=O)CC7=CC=C(O)C=C7–Inflammation/Immunology–10 mM in DMSO–P2X Receptor—-Membrane Transporter/Ion Channel–Peptides