Description

Pterinotoxin-1 is a sodium channel inhibitor peptide toxin[1].—Neuroscience-Neuromodulation–C163H251N49O53S7—-[1]Zhang Y Y, et al. Structural and functional diversity of peptide toxins from tarantula Haplopelma hainanum (Ornithoctonus hainana) venom revealed by transcriptomic, peptidomic, and patch clamp approaches[J]. Journal of Biological Chemistry, 2015, 290(22): 14192-14207.—-3969.49—-O=C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@H]1CCCCN)=O)=O)=O)=O)NC2=O)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCSC)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H]4CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)NC1=O)C(N[C@@H](CC(O)=O)C(N7[C@@H](CCC7)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H]2CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)=O)NC4=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N–Neurological Disease–10 mM in DMSO–Sodium Channel–Nav1.3;Nav1.7;Nav1.8–Membrane Transporter/Ion Channel–Peptides