Description

Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.–20°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C18H27NO9-Citation–References-[1]Zhenjun Diwu, et al. Polyfluoreno[4,5-cde]oxepine Conjugates and Their Use in Methods of Analyte Detection. US20170275418A1.-CASNumber-1393330-40-9-MolecularWeight-401.41-Compound Purity-98.0-SMILES-C#CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O-Research_Area-Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)-Target-ADC Linker;PROTAC Linkers-Isoform-Alkyl/ether Linkers;Cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related