Description

Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.–20°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C13H25NO5-Citation–References-[1]Robert Zamboni, et al. Raf-degrading conjugate compounds. WO2018200981A1.-CASNumber-1589522-46-2-MolecularWeight-275.34-Compound Purity-98.86-SMILES-C#CCOCCOCCOCCOCCOCCN-Research_Area-Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related