Description

Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.–20°C (Powder, stored under nitrogen)-Applications-Cancer-programmed cell death-Formula-C14H19NO7-Citation–References-[1]Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1.-CASNumber-1428629-71-3-MolecularWeight-313.30-Compound Purity-97.0-SMILES-O=C(ON1C(CCC1=O)=O)CCOCCOCCOCC#C-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Alkyl/ether Linkers;Cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related