Description

PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1].—–C21H31ClN6O3—-[1]Mohler MA, et, al. D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy. Thromb Haemost. 1986 Oct 21;56(2):160-4.–71142-71-7–450.96—-O=C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(CCl)=O)=O)[C@@H](CC2=CC=CC=C2)N–Cardiovascular Disease–10 mM in DMSO–PAI-1—-Metabolic Enzyme/Protease–Peptides