Description

Ponesimod-d7 (ACT-128800-d7) is the deuterium-labeled Ponesimod (HY-10569). Ponesimod-d7 (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod-d7 activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod-d7 can protect against lymphocyte-mediated tissue inflammation[1][2][3].–20°C, 3 years; 4°C, 2 years (Powder)-Applications–Formula-C23H18D7ClN2O4S-Citation–References–CASNumber–MolecularWeight-468.02-Compound Purity-96.50-SMILES-O=C1N(C2=C([2H])C([2H])=C([2H])C([2H])=C2C([2H])([2H])[2H])/C(S/C1=CC3=CC=C(OC[C@H](O)CO)C(Cl)=C3)=N/CCC-Research_Area-Others-Solubility-DMSO : 100 mg/mL (ultrasonic)-Target-Isotope-Labeled Compounds-Isoform–Pathway-Others-MCE Product type-Isotope-Labeled Compounds