Description

Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8™ AM and Quest Rhod-4™ AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor[1][2].–20°C, 3 years; 4°C, 2 years (Powder)-Applications-COVID-19-immunoregulation-Formula-N/A-Citation–References-[1]Antunes FE, et al. Gels of Pluronic F127 and nonionic surfactants from rheological characterization to controlled drug permeation. Colloids Surf B Biointerfaces. 2011 Oct 1;87(1):42-8.|[2]Peng X, et al. Poloxamer 407 Induces Hypertriglyceridemia but Decreases Atherosclerosis in Ldlr-/- Mice. Cells. 2022 May 30;11(11):1795.-CASNumber-9003-11-6-MolecularWeight-12600(Average)-Compound Purity–SMILES-CC.[H(OCH2CH2)x(OCH2CH)y(OCH2CH2)zOH].[CH3]-Research_Area-Inflammation/Immunology-Solubility-H2O : 110 mg/mL (ultrasonic)-Target-LPL Receptor-Isoform–Pathway-GPCR/G Protein-MCE Product type-Biochemical Assay Reagents