PKG inhibitor peptide (TFA)-Get quote

Description

PKG inhibitor peptide TFA is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 86 μM[1].—Cancer-Kinase/protease–C40H75F3N18O12—-[1]Bhatnagar D, et al. Synthetic peptide analogues differentially alter the binding affinities of cyclic nucleotide dependent protein kinases for nucleotide substrates. Biochemistry. 1988 Mar 22;27(6):1988-94.|[2]Chiung-Chun Huang, et al. Activation of muscarinic acetylcholine receptors induces a nitric oxide-dependent long-term depression in rat medial prefrontal cortex. Cereb Cortex. 2010 Apr;20(4):982-96.—-1057.13—-O=C(O)CC[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)N)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O–Cancer–10 mM in DMSO–PKG—-Stem Cell/Wnt–Peptides