Description

Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].–20°C, 3 years (Powder)-Applications-Cancer-programmed cell death-Formula-C37H40N4O5-Citation–References-[1]Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.-CASNumber-2149584-03-0-MolecularWeight-620.74-Compound Purity-99.0-SMILES-OCC(C=C1)=CC=C1NC([C@@H](NC([C@@H](N)CC2=CC=CC=C2)=O)CCCCNC(OCC3C4=CC=CC=C4C5=CC=CC=C35)=O)=O-Research_Area-Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)-Target-ADC Linker-Isoform-Cleavable Linker;Protease Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related